Release kinetics pdf
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چکیده
Then, drug release kinetics follows a well defined behavior in order to supply the maintenance dose enabling the attainment of the desired drug concentration.
منابع مشابه
Mathematical Modeling and Release Kinetics of Green Tea Polyphenols Released from Casein Nanoparticles
Drug release kinetics plays an important role in determining the mechanism of drug release, which in turn helps in formulating controlled/sustained release formulations.In our study, different concentrations of green tea polyphenols (GTP) were encapsulated into casein nanoparticles which showed a maximum encapsulation efficiency (76.9%) at a GTP concentration of 5 mg/mL. The casein nanopa...
متن کاملMathematical Modeling and Release Kinetics of Green Tea Polyphenols Released from Casein Nanoparticles
Drug release kinetics plays an important role in determining the mechanism of drug release, which in turn helps in formulating controlled/sustained release formulations.In our study, different concentrations of green tea polyphenols (GTP) were encapsulated into casein nanoparticles which showed a maximum encapsulation efficiency (76.9%) at a GTP concentration of 5 mg/mL. The casein nanopa...
متن کاملThe Effect of Formulation Variables on the Release Kinetics of Paracetamol Tablet Formulations.
Aim: The objective of this work was to study the effects of formulation variables on the release kinetics of paracetamol tablet formulation. Materials and Methods: Paracetamol tablets were formulated using wet granulation (WG) and direct compression (DC) using two predetermined pressures. Avicel, dicalcium phosphate (DCP) and pregelatinized starch (PGS) were used as directly compressible...
متن کاملThe Effect of HLB on the Release Profile of Atenolol from Ethyl Cellulose-coated Tablets
It is possible to alter the permeability of ethyl cellulose membrane with certain materials such as surfactants. In this study the effect of surfactant concentration and different HLB values on the release rate of atenolol from ethyl cellulose-coated tablets was evaluated. The results showed that when the concentration of surfactant increased, the rate of drug release also increased. The kineti...
متن کاملThe Effect of HLB on the Release Profile of Atenolol from Ethyl Cellulose-coated Tablets
It is possible to alter the permeability of ethyl cellulose membrane with certain materials such as surfactants. In this study the effect of surfactant concentration and different HLB values on the release rate of atenolol from ethyl cellulose-coated tablets was evaluated. The results showed that when the concentration of surfactant increased, the rate of drug release also increased. The kineti...
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تاریخ انتشار 2015